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Gender Differences in Achilles Tendon Ruptures - A Retrospective Study

Description

Achilles tendon ruptures are common injuries typically sustained during sport with higher incidence in men, though little is understood regarding sex-specific risk factors or outcomes following injury management. This cross-sectional clinical study and systematic review aimed to examine sex-specific Achilles tendon rupture incidence and outcomes following intervention. This study included patients who sustained a rupture between 2011-2021, were ≥18 years old, and who had a minimum follow-up of at least six months, and evaluated age, sex, sport involvement, mechanism of injury, and postoperative complications and revision. Separately, a systematic literature review in the PubMed, EMBASE, and Cochrane databases was performed. A total of 705 male and 158 female patients were included in this retrospective study. 71.1% of men and 52.5% of women sustained a sports-related rupture (p< 0.001), with sport involvement demonstrating a positive correlation with revision rate (coefficient=0.09, p=0.02). A total of 21 studies with 250,907 patients (87,514 male, 35,792 female) were included in the systematic review. All studies revealed an increased incidence of ATR in men. Functional outcomes were worse in women, and female sex was an independent risk factor for postoperative complications and need for revision surgery. This study demonstrated a higher incidence of sports-related ATR in men than women, likely related to their higher ball sport participation. Although the retrospective analysis did not find a significant difference in complication or revision rates, the systematic review demonstrates poorer functional outcomes, with increased likelihood for postoperative complication and revision surgery in women as compared to men.

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Author

H H

Hayden Hartman

Medical Student

DeBusk College of Osteopathic Medicine

A C

Alexis Cacace

Research Fellow

Foot and Ankle Research and Innovation Lab (FARIL), Harvard Medical School

H L

Hadley Leatherman

Medical Student

Foot and Ankle Research and Innovation Lab (FARIL), Harvard Medical School

S A

Soheil Ashkani-Esfahani

Orthopaedic Surgeon

Foot and Ankle Research and Innovation Lab (FARIL), Harvard Medical School

D G

Daniel Guss

Orthopaedic Surgeon

Massachusetts General Hospital, Harvard Medical School

G W

Gregory Waryasz

Orthopaedic Surgeon

Massachusetts General Hospital, Harvard Medical School

C W

Christopher W. DiGiovanni

Orthopaedic Surgeon

Massachusetts General Hospital, Harvard Medical School

A L

Arianna L. Gianakos

Orthopaedic Surgeon

Yale Medicine, Orthopaedics and Rehabilitation

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